Week 7b

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b. Heterogeneity within populations and subgroups

(continued in week 8)


Idea: How people respond to treatment may vary from one subgroup to another--When is this a matter of chance or of undetected additional variables? How do we delineate the boundaries between subgroups?

 

Cases: Forms of breast cancer, Low dose aspirin and prevention of cardiovascular events, Statistical concerns

 

Readings: Regan 2005, Eikelboom 2003, Gum 2003, Nelson 2005, Lagakos 2006

 

Copyright ©2010 Peter Taylor, Ph.D.